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L’Oréal-Backed Biotech Company Debut Raises $20 Million

Yesterday, according to report, biotech beauty company Debut has raised $20 million in a new funding round to accelerate its AI-powered ingredient discovery platform and expand its formulation business across Asia. The San Diego-based startup, which has now secured a total of $85 million to date, attracted backing from Fine Structure Ventures, EDBI, Wealthberry, L’Oréal’s BOLD fund, GS Futures, Sandbox Industries, and Material Impact, among others.

The fresh capital will support the advancement of skin longevity innovation and the scaling of its operations in both the U.S. and Asia. Central to Debut’s strategy is the development of next-generation ingredients designed to target the 14 hallmarks of aging. “Debut is laser-focused on staying at the forefront of skin care innovation and bringing cutting-edge biotech to every beauty brand with the highest-performing and most differentiated ingredients,” said Joshua Britton, founder and CEO of Debut.

Britton emphasized the shift in industry language from “antiaging” to “skin longevity,” noting the scientific challenge of addressing multiple biological markers of skin aging. Debut leverages AI and biotechnology to screen billions of potential compounds, identifying those that can meaningfully impact skin health.

The company is also preparing to launch in Asia, beginning with Singapore, where it will partner with local brands to create customized longevity-focused ingredients and formulations tailored to regional needs. “AI combined with an understanding of skin biology enables the creation of custom formulation solutions for different geographies that has previously not been possible,” Britton said.

In mid-2024, the company struck a deal with L’Oréal to co-develop more than a dozen bio-identical alternatives to conventionally sourced ingredients across categories including skin care, hair care, color cosmetics, and fragrance. The partnership marked a significant milestone following L’Oréal’s $40 million investment in Debut in June 2023.

Complementing its B2B strategy, Debut also launched its own skin care line, Deinde, in January 2024, which Britton said is performing strongly and on track to surpass growth expectations this year.

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