Recently, The European Chemicals Agency (ECHA) has announced a new initiative to explore a method that may replace aquatic toxicity tests currently requiring fish. This initiative involves the Fraunhofer Institute in Germany, which will assess the potential of the Fish Embryo Toxicity (FET) test, an approach that could bypass animal testing. The FET test focuses on fish embryos, a life stage that is not protected under EU animal welfare regulations, making it a potential non-animal alternative in regulatory hazard assessments.
In ecotoxicology, fish play a key role in testing both short- and long-term chemical toxicity, as well as determining toxicological actions like endocrine disruption in aquatic environments. The FET test, especially when combined with transcriptomics (the study of an organism’s RNA), might provide a more humane method of obtaining similar data without using mature fish.
The EU’s stance on animal testing in cosmetics remains complex. Ingredients in cosmetics cannot be used if they have been tested on animals to comply with EU consumer safety regulations. However, they must also meet the standards of REACH (Registration, Evaluation, Authorisation, and Restriction of Chemicals), a regulation that exists to safeguard human health and environmental safety. REACH occasionally mandates additional data on cosmetic ingredients, even when this requires animal testing, creating a conflict with the EU’s consumer-focused ban on animal testing for cosmetics.





