The market for recombinant collagen is boiling again. Chuangjian Medical has independently developed Type III recombinant human collagen, and Xiu Li Ke has launched an injectable recombinant Type III human collagen solution. It can be seen that this year, both upstream suppliers and brand owners have made new breakthroughs in the research and application of recombinant collagen, especially Type III collagen.
In fact, Type III collagen, also known as “baby collagen,” determines the elasticity and delicacy of the skin, and has long been a focus in the market. CHAILEEDO has learned that Natural Health uses 100% human-derived Type III collagen and the polar yeast HiMurchaSin™ as the main ingredients, and has launched the CHANDO Himalaya Extravagance Rejuvenation Collagen Cream, a specialized anti-aging cream for sensitive skin. It is revitalizing the sector of anti-aging products for sensitive skin with its outstanding performance.
So why has Type III collagen become the “flagship” of the recombinant collagen market? And how has CHANDO Himalaya Extravagance Rejuvenation Collagen Cream become a new engine igniting the sector of anti-aging products for sensitive skin?
Type III Collagen: The Chosen One for Anti-Aging in Sensitive Skin
When people talk about skin aging, they can’t avoid mentioning the term “collagen loss.” This is because collagen is the most abundant protein in the human body, with 90% of it found in the skin and bones. It plays a crucial role in maintaining and supporting the normal physiological functions of cells, tissues, and organs, as well as repairing damage. It also plays an important role in the formation of skin aging.
Currently, research has identified 29 types of collagen in the human body, including Type I, II, III, IV, and V. Among them, skin collagen is mainly composed of Type I and Type III. If Type I collagen is the “skeleton” that supports the skin, then Type III collagen is the “spring” within the skin. Both are indispensable for achieving plump and elastic skin.
However, unlike Type I collagen, which has a high content, slow loss rate, and the ability to regenerate spontaneously, Type III collagen is present in high amounts (around 80%) only in infant skin and rapidly decreases to only 15%-20% as one ages. Moreover, it cannot be regenerated. As Type III collagen continues to diminish, it’s as if the elastic spring loses its resilience, resulting in the formation of wrinkles and the presence of skin creases.
In simple terms, Type III collagen is a youthful and newborn collagen that helps maintain and repair skin elasticity, playing a role in wrinkle reduction and skin firming. Once adulthood is reached, Type III collagen does not return, and its loss can only be replenished externally.
Because Type III collagen governs youthfulness and is both important and scarce, it has always been a focal point of research. In recent years, with the development of modern biotechnology and synthetic biology, functional proteins obtained through the recombination and optimization of the original gene sequence of human Type III collagen have been created. These proteins exhibit 100% similarity to the human Type III collagen sequence, offering advantages such as easy absorption, no rejection or allergic reactions, and increased activity. They have been proven to be effective and safe in skin repair for burn patients and in aesthetic anti-aging injections.
It is evident that recombinant human Type III collagen is not only an excellent anti-aging agent but also a “chosen one” for anti-aging in sensitive skin due to its compatibility with the human body. Recombinant human Type III collagen is gradually gaining recognition in the cosmetics industry.
It is known that Natural Health is one of the first domestic skincare brands in China to apply recombinant human Type III collagen in their facial cream products. In September of last year, the CHANDO Himalaya Extravagance Rejuvenation Collagen Cream was officially launched. Unlike other collagen creams that solely focus on anti-aging or repair, CHANDO Himalaya Extravagance Rejuvenation Collagen Cream takes a formulaic approach of “external repair and internal replenishment,” specifically targeting the anti-aging concerns of sensitive skin and post-aesthetic treatment individuals.
Dual “True” Collagen: External Repair and Internal Supplementation
It is well known that the effectiveness of a skincare product relies not only on the activity and quality of its ingredients but also on the scientific nature of its formulation. The birth of CHANDO Himalaya Extravagance Rejuvenation Collagen Cream is based on the brand’s commitment to technology and the meticulous development of each product.
Firstly, in terms of ingredient selection, CHANDO Himalaya Extravagance Rejuvenation Collagen Cream utilizes highly active collagen obtained by complete extraction of Type III collagen DNA fragments. This Type III collagen is produced under the same standards as medical devices, ensuring “true” collagen and true effectiveness.
Secondly, through the use of a new generation of yeast fermentation patented technology, hydroxyproline-modified collagen is prepared. This type of collagen protein can form hydrogen bonds and self-assemble into a fibrous structure, meeting the basic requirements for the formation of a complete triple-helix collagen body. The triple-helix structure has always been a key indicator of collagen protein compatibility and functionality.
It is worth mentioning that the brand, in collaboration with partners, has deciphered the core “code” of collagen and identified the RGD site of Type III collagen, which can effectively promote cell adhesion to biomaterials. With the support of multiple advanced technologies, the recombinant human Type III collagen protein in CHANDO Himalaya Extravagance Rejuvenation Collagen Cream is more core-centric, highly active, deeply penetrating, and anti-aging.
Specifically, CHANDO Himalaya Extravagance Rejuvenation Collagen Cream combines dual 100% recombinant human Type III collagen with different molecular sizes. This formulation not only allows deep penetration within one hour¹, reaching the deeper layers of the skin but also overcomes the limitations of single collagen in terms of efficacy. The larger molecular collagen accelerates the repair of the skin barrier, while the 5kDA small molecule Type III collagen replenishes Type III collagen and promotes the production of Type I collagen, resulting in quickly rebounding and plump skin.
Additionally, CHANDO Himalaya Extravagance Rejuvenation Collagen Cream also incorporates the exclusive patented ingredient HiMurchaSin™, derived from polar yeast by Natural Health. This ingredient activates the regeneration of collagen precursor cells and doubles the production of collagen. This unique formulation is designed to address the characteristics of sensitive skin that is prone to damage and rapid collagen loss, achieving accelerated repair and supplementation.
Qin You, the Director of the International Skincare Laboratory at Natural Health, stated, “In addition to key repair and anti-aging core ingredients, when developing this collagen cream, we controlled the overall formula to be concise and safe, and specially designed a lightweight and dense texture that allows for rapid absorption of active ingredients upon direct application. Importantly, its excellent spreadability prevents additional damage to sensitive skin caused by excessive rubbing.”
According to third-party experimental data, CHANDO Himalaya Extravagance Rejuvenation Collagen Cream achieves 6 hours of sensitivity repair and lightens 8 major fine lines in 7 days. In terms of collagen promotion, CHANDO Himalaya Extravagance Rejuvenation Collagen Cream can stimulate Type I collagen production by 87.88% and Type III collagen production by 198%, surpassing other collagen creams on the market and demonstrating outstanding repair and anti-aging effects.
It is reported that since its launch, CHANDO Himalaya Extravagance Rejuvenation Collagen Cream has received positive feedback. It has not only gained recognition from dermatology experts and medical doctors in top hospitals but also received praise from many consumers who consider it their “go-to cream” for sensitive skin and anti-aging.
Market of CHANDO’s Innovative Sensitive Skin Anti-Aging Products
Public data shows that approximately 36.1% of women in China have sensitive skin issues. CHAILEEDO intelligence data also shows that the market size of sensitive skin care reached 29 billion yuan in 2022, with a year-on-year growth rate of 20.8%. In the past five years, the growth rate of the sensitive skin care market has consistently outperformed the overall skincare market growth rate.
Moreover, improper lifestyle and skincare habits, combined with the expanding consumer base of medical aesthetics, indicate that the sensitive skin population is expected to continue growing. Another change is that sensitive skin consumers are no longer satisfied with basic repair and maintenance effects; anti-aging for sensitive skin has become a priority.
From a market perspective, there are many players in the field of sensitive skin anti-aging, but there has yet to emerge a benchmark brand or a phenomenally successful product. For CHANDO, this represents both a challenge and an opportunity.
Recognizing that the approach of using aggressive ingredients to “break down and rebuild” the skin can have adverse effects on sensitive skin, CHANDO has adopted a strategy of “repairing while supplementing.” Through the use of dual 100% recombinant human Type III collagen and polar yeast HiMurchaSin™, CHANDO nourishes the skin and establishes a protective barrier, providing a gentle and effective anti-aging solution for sensitive skin.
By daring to challenge traditions and once again demonstrating the concept of “leading by half a step,” CHANDO showcases the accumulated research and development efforts of the CHANDO Group over the years. The group has established six major research platforms: “Consumer Big Data Insights, Oriental Dermatology Research, Ingredient Selection and Development, Formula Technology, Packaging Development, and Sensory Evaluation,” ensuring the continuous development of safe and reliable products. Polar yeast HiMurchaSin™ is one of the fruits of the group’s research efforts.
CHANDO Himalaya Extravagance Rejuvenation Collagen Cream embodies CHANDO’s consistent product development philosophy of healing and rejuvenating, and anti-aging at the cellular level. The pioneering innovation of this flagship brand may elevate the field of sensitive skin anti-aging and establish a new benchmark in this domain.
