Chinese “No.001” Ingredient is Expanded with Anti-aging Effect

The first new raw material “N-acetylneuraminic acid” (commonly known as bird’s nest acid) registered on the Cosmetic Raw Material Recording Information Platform of National Medical Products Administration China has completed the expansion. The purpose of the raw material is anti wrinkle agent, skin protector, moisturizer and antioxidant, and can be used for skin maintenance and care of the whole body.

Recently, according to the China National Medical Products Administration’s Cosmetic Raw Material Recording Information Platform, after the opening of the new raw material filing, China’s first filing new raw material “N-acetylneuraminic acid” has completed the expansion. On the basis of the original moisturizing agent, it has four new usage purposes: anti-wrinkle agent, skin protector, antioxidant. At the same time, heavy metal indicators and strain numbers are also added.

The successful expansion of the efficacy of “N-acetylneuraminic acid” means that the raw material will have a wider application space and higher application value.

According to the China National Medical Products Administration, “N-acetylneuraminic acid” is a non-animal and plant raw material, commonly known as bird’s nest acid, bird’s nest element, sialic acid. The purpose of use before the expansion is a moisturizing agent, which can be used for whole body skin care. care. Its maximum allowable concentration when used in cosmetics is 2%.

It is reported that “N-acetylneuraminic acid” is the first new raw material that has been approved for filing in China, and the first new raw material that has successfully expanded its efficacy. The raw material comes from a Chinese biotechnology company – Wuhan Zhongke Optics Valley Green Biotechnology Co.,Ltd. (hereinafter referred to as “Zhongke Optics Valley”).

It is worth noting that Zhongke Optics Valley and its parent company Jiabiyou Biotechnology (Wuhan) Co., Ltd. (hereinafter referred to as “Jiabiyou”) have been sued before. According to the Jiabiyou announcement, Higrand Biotech (hereinafter referred to as “Higrand”) claimed in the lawsuit that Jiabiyou and Zhongke Optics Valley jointly obtained the relevant information of Higrand through improper means, including combination of strains, production and commercial technical secrets of N-acetylneuraminic acid. Zhongke Optics Valley uses this technology to produce and sell products that are identical or substantially identical to those of Higrand. Therefore, in the trade secret dispute of Higrand, a lawsuit was filed against Jiabiyou and Zhongke Optics Valley.

From the perspective of regulations, the usage of sialic acid in cosmetics is exclusive in China. Some people in the Chinese industry said that during the monitoring period, the new cosmetics raw materials belong to the owner. In other words, during the monitoring period of sialic acid raw materials, if a brand wants to use new raw materials, it must be approved and authorized by the filing enterprise before it can use the methods and means of preparing and extracting raw materials of the filing enterprise.

Therefore, if there is a problem with the patent ownership of raw material preparation, it may affect the use of sialic acid raw materials in Chinese cosmetics in the next three years. So the prosecution of Zhongke Optics Valley and Jiabiyou will affect the application of “N-acetylneuraminic acid” in cosmetics?

In this regard, a relevant person from Jiabiyou said: “The dispute with Zhongke Hongji is mainly in the field of food. Sialic acid as a cosmetic raw material is independently declared by the company, and the production and preparation of raw materials are strictly in compliance with regulations.” He introduced that sialic acid is a crystalline product of N-acetylneuraminic acid with a purity of more than 98% obtained from glucose and corn syrup through fermentation, filtration, sterilization, hydrolysis, purification and other steps by Escherichia coli. The raw material can be used as a moisturizer for skin maintenance and care of the whole body.

“It is certain that the use of sialic acid as an exclusive raw material in cosmetic products fully complies with regulations, and has no impact on the production and use of cosmetic raw materials, nor will it affect the use of brands.” The person in charge added.

At present, “N-acetylneuraminic acid” has been used in related cosmetics.




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