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Solving Fatigue-Induced Aging, Chando’s Star Product Upgraded for the Sixth Time!

The dispute over ingredients in Chinese skincare has long entered the second half.

As one brand after another begins to overcome the challenge of “ingredient bottleneck,” as “Chinese ingredients” gradually become the “standard configuration” for domestic beauty brands, and as independent research and scientific patents are no longer something new, how will Chinese brands continue the story of ingredients? The answer given by Chando, which has been deeply involved in fermentation technology research for 11 years, is to closely focus on the real needs of users, continuously innovate and iterate, and constantly rejuvenate the brand with new vitality.

Recently, Chando’s soul ingredient “HiMurchaSin” has achieved a revolutionary technological breakthrough, and the first intelligent fermentation material in China, “HiMurchaSin® filtrate + cytoplasm,” has made a grand debut. While iterating its ingredients, Chando has also collaborated with authoritative dermatologists to define “fatigue-induced aging” for the first time. Through in-depth research on the mechanism of skin aging, it directly targets the points of fatigue-induced aging and officially launches the sixth generation of Chando’s little purple bottle essence, leading the anti-aging market into a new stage. It can be said that a new war against aging has quietly begun.

HiMurchaSin get a revelution!

In today’s era where ingredients reign supreme, a significantly effective flagship ingredient can even influence the entire trajectory of a brand’s development. Take the widely used “yeast derivative” in skincare products, for example. Several international brands, including SK-II, Estée Lauder, and La Mer, have introduced flagship products with yeast ingredients at their core. Many domestic brands have also seized this trend and launched “dupes” of these popular products.

However, from a long-term perspective, merely “following” is far from enough. Only by possessing completely independent intellectual property rights for ingredients can a brand gain market initiative in the battle of ingredients.

For this reason, as early as 2013, Chando Group began collaborating with the Institute of Microbiology at the Chinese Academy of Sciences to conduct research on microbial fermentation. They even sent yeast strains aboard the Shenzhou 10 spacecraft to develop space yeast. Simultaneously, Chando delved deep into the heartland of the Himalayas, using local highland resources as a basis to isolate 558 strains of polar bacteria and establish the Himalayan characteristic strain library.

In 2021, among the 558 polar bacterial strains, Chando selected a unique strain and successfully developed a yeast ingredient called HiMurchaSin® with powerful repair and cellular regeneration capabilities through dedicated fermentation technology research. This not only broke the overseas monopoly on yeast ingredient prices but also further narrowed the gap between domestic and foreign ingredient research and development.

However, for Chando, an innovator in the field of anti-aging research, the birth of HiMurchaSin® is not the end. They are still on the path of in-depth research in the field of biological fermentation. As a result, HiMurchaSin® has officially begun iteration and introduced “HiMurchaSin® cytoplasm” based on the filtrate, initiating a new round of innovation in anti-aging technology.

So, what upgrades does HiMurchaSin® cytoplasm bring with its new appearance?

Simply put, HiMurchaSin® filtrate is like “chicken broth,” while HiMurchaSin® cytoplasm is more like “chicken meat.” Through the fifth-generation “intelligent fermentation” technology, Chando uses external forces to disrupt the cell membrane and cell wall, directly releasing various nutrients from yeast cells. This not only reduces the molecular weight of the cytoplasm but also retains as many active byproducts generated during fermentation as possible.

Experimental test results show that HiMurchaSin® filtrate and cytoplasm can penetrate the depths of the skin within 8 hours, reaching the five layers of the skin, including the stratum corneum, transparent layer, and granular layer. They achieve eight times the promotion of cellular-level regeneration in the basal layer, helping cells recover energy from within and restoring the skin’s plumpness. This leads to a multi-layered anti-aging effect and overall rejuvenation throughout the entire dermis.

Moreover, compared to other classic anti-aging ingredients, HiMurchaSin® cytoplasm also demonstrates superior effectiveness. Research reports show that compared to boswellin, HiMurchaSin® cytoplasm has a stronger ability to promote type IV collagen production. Compared to the cytoplasm of split yeast fermentation products, it exhibits stronger epithelial and dermal cell proliferation effects. Furthermore, compared to retinol, HiMurchaSin® cytoplasm has a stronger ability to promote the new growth factor KI67.

It can be said that the launch of HiMurchaSin® cytoplasm is a revolutionary breakthrough in the current domestic yeast ingredient scene. It is also a significant advancement in “Chinese ingredients,” showcasing the innovative power of Chinese brands to the world.

To combat “fatigue-induced aging,” Chando Time Frozen Essence undergoes further iteration

The structural upgrade is just one aspect of the HiMurchaSin® iteration. More importantly, HiMurchaSin® filtrate + cytoplasm starts from the root cause of aging and grasps an important factor in the current poor skin condition of the general population: “fatigue-induced aging.”

UV exposure, air pollution, endless meetings, never-ending work, the chaos of life… These external and internal pressures accumulate in the body, causing multiple layers of the skin to become “overworked.” Prolonged fatigue leads to continuous stress responses in cells, triggering the secretion of various stress factors, disrupting the internal environment homeostasis, and inhibiting cell proliferation.

In response to this, the research and development team of Chando, in collaboration with Professor Liu Wei, a consultant at the Chinese Physicians Association Dermatology Committee, and Dr. Huang Yan from Tsinghua University, jointly published a paper titled “Fatigue-Induced Aging: Stress, Reactive Oxygen Species, and Inflammation,” detailing the mechanism of “fatigue-induced aging” and proposing professional solutions.

In short, when the rate of cell regeneration cannot keep up with the rate of cell turnover, the aging process naturally accelerates, leading to various skin problems. At this point, replenishing cellular energy and promoting cell regeneration become important ways to combat fatigue-induced aging. In fact, these are also the underlying logic behind the iteration of Chando’s products.

It is understood that the newly launched sixth-generation Chando Time Frozen Essence is based on “fatigue-induced aging,” combining the latest iteration ingredient HiMurchaSin® cytoplasm with the original formula to replenish cellular energy and restore cell renewal from within. It addresses the process of fatigue-induced aging at its root, providing a solution from Chando for consumers under high pressure.

Research reports show that a drop of HiMurchaSin® filtrate + cytoplasm contains 2 million yeast cell essences and is rich in 940 highly concentrated active small molecules. The relative content of adenosine in HiMurchaSin® cytoplasm exceeds 70%2, which can help cells replenish lost energy and promote cell regeneration. The combination of the two not only reaches the depths of the skin, activating eight times the cellular-level regeneration, making the skin smooth and plump, but also achieves rapid repair within one hour.

In addition, the sixth-generation Chando Time Frozen Essence also adds 99% pure sulforaphane at a 10 times higher concentration, giving the new generation of Chando Time Frozen Essence stronger antioxidant capacity. It is also formulated with small-molecule peptides and tranexamic acid to replenish the antioxidant matrix and achieve a gentle and radiant effect.

Results from third-party human efficacy verification show that after using the sixth-generation Chando Time Frozen Essence, over 97% of subjects acknowledge the immediate firming effect. After 12 hours of use, skin elasticity increases by 10%, and after 28 days of use, skin color value improves by 6.04%.

Renewal in the Anti-Aging Market: Chando Leading the Way

According to CHAILEEDO data, the market size of anti-aging cosmetics with efficacy reached 302.89 billion yuan in 2023, a year-on-year growth of 30.5%. The market share increased by 7.4 percentage points, and the average price of products was 294.55 yuan, which is 3.1 times the overall average price of cosmetics in China. Undoubtedly, in this market that has long become saturated, only with updated technology, concepts, and ingredients can one continue to dominate the high ground.

Of course, compared to international brands that have already accumulated several decades or even hundreds of years in basic research, domestic brands still have room to catch up in terms of independent research and development capabilities. However, progress in the industry always requires pioneers, and Chando is an important player in this regard.

This time, Chando starts with “fatigue-induced aging” and introduces the revolutionary ingredient HiMurchaSin® filtrate and cytoplasm. It has launched the “True Yeast Essence for Fatigue-Induced Aging in Chinese Women,” which not only provides a new approach to scientific anti-aging but also offers new development ideas for the current anti-aging market revolution.

In fact, prior to the release of the sixth-generation Chando Time Frozen Essence, Chando and its Time Frozen Essence series have always been leaders in the anti-aging market. From the first generation, which focused on repairing skin damage, to introducing the technology of time suspension and hibernation, adding Himalayan red algae for the first time, proposing overnight skin anti-aging, and the first addition of HiMurchaSin… Chando has always been at the forefront of the anti-aging market, leading the way by being “half a step ahead.”

Behind the identity of the “leader” lies Chando’s 23 years of product development, 11 years of deep cultivation in the field of biological fermentation, and the collective participation of over 100 scientists. Public information shows that up to now, Chando Group has produced more than 30 significant scientific research reports, with 9 published SCI papers and 47 IFSCC papers. At the same time, Chando released the “Fermentation Technology White Paper” last year, providing a complete path for fermentation technology iteration in the cosmetics industry.

“The vision of Chando Group is to become China’s leading and world-leading technology beauty company.” This is the declaration made by Zheng Chunying, Chairman and President of Chando Group, at the beginning of this year’s annual meeting, and it is also what Chando Group has always upheld.

This time, Chando has provided a new answer for the anti-aging market revolution with innovative ingredients. In the future, Chando will undoubtedly continue to bring new surprises to the anti-aging market.

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